Health and population effects of rare gene knockouts in adult humans with related parents
Work
Year: 2016
Type: article
Abstract: Rare gene knockouts in adult humans On average, most people's genomes contain approximately 100 completely nonfunctional genes. These loss-of-function (LOF) mutations tend to be rare and/or occur only... more
Source: Science
Authors Vagheesh M. Narasimhan, Karen A. Hunt, Dan Mason, Christopher L. Baker, Konrad J. Karczewski +31 more
Institutions Wellcome Sanger Institute, Queen Mary University of London, Bradford Teaching Hospitals NHS Foundation Trust, National Health Service, Jackson Laboratory +15 more
Cites: 59
Cited by: 291
Related to: 10
FWCI: 29.56
Citation percentile (by year/subfield): 92.31
Topic: Genomics and Rare Diseases
Subfield: Genetics
Domain: Life Sciences
Open Access status: bronze