A branched-chain amino acid metabolite drives vascular fatty acid transport and causes insulin resistance
Year: 2016
Type: article
Source: Nature Medicine
DOI: 10.1038/nm.4057
Authors: Cholsoon Jang, Sungwhan F Oh, Shogo Wada, Glenn C Rowe, Laura Liu, Mun Chun Chan, James Rhee, Atsushi Hoshino, Boa Kim, Ayon Ibrahim, Luisa G Baca, Esl Kim, Chandra C Ghosh, Samir M Parikh, Aihua Jiang, Qingwei Chu, Daniel E Forman, Stewart H Lecker, Saikumari Krishnaiah, Joshua D Rabinowitz, Aalim M Weljie, Joseph A Baur, Dennis L Kasper, Zoltan Arany
Language: English
Subfield: Endocrinology, Diabetes and Metabolism
Field: Medicine
Domain: Health Sciences
Open Access status: green
Funders: National Institutes of Health, National Institute on Aging, National Heart, Lung, and Blood Institute, National Institute of General Medical Sciences, National Institute of Allergy and Infectious Diseases, National Institute of Diabetes and Digestive and Kidney Diseases, National Institute of Arthritis and Musculoskeletal and Skin Diseases
Awards: Targeting the Endothelium in Sepsis, G1384588277, G1419042683, G143592787, NKT Cell Mediated Immunoregulation by Symbiotic Gut Microbial Glycosphingolipids, G171471675, Molecular Mechanisms of Rapamycin's effects on Health and longevity., G2513047960, G2728703951, G3036318192, G3176217760, PGC-1 Coactivators in Muscle Angiogenesis and Ischemia, G3933042922, Training Program in Cardiovascular Research, G5244387415, G5478978553, G5524044861, G5881945070, Integrative Metabolic Adaptations to Enviromental and Nutritional Challenge, G645141164, G7227154987, Research Training for Anesthetists, University of Pennsylvania Diabetes Research Center, Mitochondria and metabolism in kidney disease, Infectious Disease and Basic Microbiological Mechanisms, G910596814, G914811333
OpenAlex ID: W2294856235