Impact of Donor Activating KIR2DS5 and KIR2DS2 on Outcome of Allogeneic Hematopoietic Cell Transplantation (AlloHCT) in Patients with Acute Myeloid Leukemia (AML)
Year: 2016
Type: article
Study design: Observational Study
Abstract: Donor activating KIR 2DS1 and 3DS1 genes and donor KIR B haplotype have been previously associated with reduced relapse rate and improved overall survival, but not with non-relapse mortality (NRM) and Graft vs Host disease (GvHD) in AML patients (pts) undergoing AlloHCT. Here we report the effect of donor KIR status on NRM and GvHD in AML patients undergoing AlloHCT.
Institution: City Of Hope National Medical Center
Language: English
Subfield: Hematology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Estimated APC paid: $3,650
OpenAlex ID: W2299846450