Development of the diagnostic system of Alzheimer-type dementia using eye movement
Year: 2002
Type: article
Abstract: In the present study, we aimed at developing a simple evaluation system for Alzheimer-type dementia patients using eye movement; which focused on the vision cognitive impairment in Alzheimer-type dementia patients. It has been reported that there are some vision cognitive impairments e.g. smooth-pursuit, stereoscopic vision et al in Alzheimer-type dementia patients. In this study, we investigated horizontal conjugate eye movement between Alzheimer-type dementia patients and healthy elderly people and examined parameters with which Alzheimer-type dementia patients is discriminated from healthy elderly people. Horizontal conjugate eye movement was induced by a target which carries out horizontal movement. The set-up parameters are the latency, the ratio of velocity of smooth- pursuit, the average amplitude of saccades and the total amplitude of saccades. As a result, among the 2 groups, significant difference was acquired according to the average amplitude of saccades and the total amplitude of saccades (P<0.01) . Therefore, it is suggested that the evaluation system using eye movement is useful for the distinction of Alzheimer-type dementia patients and healthy elderly people.
Authors: Yuko Kawakami, Xuemin She, Yi Guo, Shogo Fukushima, Shuji Murakami, Yasuhiro Kawase, Ichiro Fukumoto
Language: English
Subfield: Psychiatry and Mental health
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2299999846