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The relationship between obesity, pregnancy, and levels of indoleamine 2,3-dioxygenase

Year: 2016

Type: article

Abstract: For a successful pregnancy to occur, foreign genetic material such as the allogeneic fetus must be tolerated within the maternal host. Indoleamine 2,3-dioxygenase (IDO) is an enzyme induced by pro-inflammatory cytokines that has been shown to be key to this process. Obesity as a pro-inflammatory state is associated with poor obstetric outcomes. The primary objective of this study is to investigate the relationship between obesity and IDO activity.

Source: Proceedings in Obstetrics and Gynecology

DOI: 10.17077/2154-4751.1301

Authors: Eric M Tyler, Donna A. Santillan, Sabrina M. Scroggins, Eric J. Devor, Wendy S. Hamilton, Stephen K. Hunter, Mark K. Santillan

Institution: University of Iowa Hospitals and Clinics

Language: English

Topic: Reproductive System and Pregnancy

Subfield: Immunology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W2302342968

FWCI:

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