Work

Tumor Regression and Allograft Rejection after Administration of Anti–PD-1

Year: 2016

Type: article

Study design: Case Report

Abstract: Cancers, especially skin cancers, may develop in patients undergoing solid-organ transplantation who receive long-term immunosuppression. The use of anti–PD-1 in one such patient produced an antitumor response but led to rejection of the transplanted kidney.

Source: New England Journal of Medicine

DOI: 10.1056/nejmc1509268

Authors: Evan J. Lipson, Serena M. Bagnasco, Jack Moore, Sekwon Jang, Manisha J. Patel, Andrea A. Zachary, Drew M. Pardoll, Janis M. Taube, Charles G. Drake

Institutions: Johns Hopkins University, MedStar Georgetown University Hospital

Language: English

Topic: Cancer Immunotherapy and Biomarkers

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: National Institutes of Health, National Cancer Institute

Awards: G1165598027, G2491929434, PD-1/PD-L1 modulation in cancer therapy

OpenAlex ID: W2303235652

FWCI: 20.86

Cites: 5

Cited by: 278

Related to: 10