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Treg cells: a potential regulator for IL-22 expression?

Year: 2014
Type: article
Abstract: Inteleurkin-22 (IL-22) is a IL-10 family cytokine member and is mainly produced by innate lymphoid cells (ILCs), Th17 cells, and Th22 cells. Previous studies have indicated that IL-23 and several transcription factors, including STAT3, RORγt, and the AhR are important stimulus. Recently, there is emerging evidence that Tregs can regulate IL-22 expression. In the review, we discuss the updated advancement on Tregs function and its regulatory role on IL-22 expression.
Institutions: Sun Yat-sen University, Second Affiliated Hospital of Zhejiang University, Zhejiang University, Tongji University, Pennsylvania State University, Shanghai East Hospital
Language: English
Subfield: Immunology
Open Access status: green
OpenAlex ID: W2303913103
FWCI: 0.986
Cites: 65
Cited by: 22
Related to: 10