Year: 2014
Type: letter
Abstract: read the paper by Sevket BALTA and cols. and thanks for your interest in our study entitled "Red Cell Distribution Width in Subclinical Hypothyroidism" (1). As we mentioned in the discussion part, the RDW can be affected by some disease conditions such as recent blood transfusion, renal dysfunction, hepatic dysfunction, anemia related nutritional deficiencies (i.e. iron, vitamin B 12 , and folic acid), bone marrow dysfunction, inflammatory diseases, chronic or acute systemic inflammation (2-5) and some medications ( And this point could be one of the major limitations of our paper. So, we tried to gather other multiple potential confounding factors as much as possible and to adjust confounding factors. And the reason what the participants comprised healthy subjects with no known systemic diseases and who were not taking any medication that may affect thyroid function, and were not pregnant or within the first year of the postpartum period is to rule out the confounding factors. Because of this aspect your paper pointed out, in fact, more investigations and prospective studies are needed to clarify the relations between RDW and subclinical hypothyroidism before application in the clinical field.
Authors: Hea Min Yu, Kang Seo Park, Jae Min Lee
Language: English
Subfield: Endocrinology, Diabetes and Metabolism
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W1966045356