Year: 2010
Type: article
Abstract: The objective of the present study was screening of 3hydroxy-3-methyl glutaryl Co A (HMG CoA) reductase inhibitor producing marine actinomycetes.A total of 65 morphologically different actinomycetes were screened for HMG CoA reductase inhibitor production in a two stage submerged fermentation and evaluated for HMG CoA reductase inhibitor activity by agar diffusion and thin layer chromatography technique using lovostatin as a control.Among 65 marine Actinomycete strains, only one strain produced HMG Co A reductase inhibitor.
Author: Phani Bhushan Srinu
Language: English
Subfield: Applied Microbiology and Biotechnology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W2306716432
