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Abstract 5494: Novel 6-substituted pyrrolo[2,3-d]pyrimidine thienoyl antifolate regioisomers target folate receptor alpha positive ovarian cancer cells via inhibition of de novo purine nucleotide biosynthesis.

Year: 2013

Type: conference-abstract

Source: Cancer Research

DOI: 10.1158/1538-7445.am2013-5494

Authors: Shermaine K. Mitchell-Ryan, Lei Wang, Steven Orr, Sita Kugel, Christina Cherian, Aleem Gangjee, Larry H. Matherly

Institutions: Wayne State University, Duquesne University, The Barbara Ann Karmanos Cancer Institute, Massachusetts General Hospital

Language: English

Topic: Synthesis and biological activity

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: closed

OpenAlex ID: W2312907617

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