Work

Porcine cancer models for translational oncology

Year: 2014

Type: article

Abstract: Large-animal cancer models are needed to advance the development of innovative and clinically applicable tumor diagnostic, therapeutic, and monitoring technologies. We developed a genetically modified porcine model of cancer based on a TP53 mutation, and established its utility for tracking tumorigenesis in vivo through non-invasive clinical imaging approaches.

Source: Molecular & Cellular Oncology

DOI: 10.4161/23723548.2014.969626

Authors: Jessica C. Sieren, Dawn Quelle, David K. Meyerholz, Christopher S. Rogers

Institutions: University of Iowa, University of Iowa Holden Comprehensive Cancer Center, University of Iowa Health Care, Exemplar Genetics (United States)

Language: English

Topic: Veterinary Oncology Research

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $1,590