Work

Cholecystokinin-1 receptor antagonists: 5-hydroxy-5-aryl-pyrrol-2-ones as anticancer agents

Year: 2016

Type: article

Abstract: Hydroxy-pyrrolones, which were potent CCK1R antagonists, showed nanomolar in vitro activity and anticancer activity in vivo for colon and pancreatic cancer.

Source: MedChemComm

DOI: 10.1039/c6md00052e

Authors: E. Lattmann, S. T. Russell, C. H. Schwalbe, A. Shortt, P. N. Balaram, E. Theochari, M. Alharbi, R. Narayanan, P. Lattmann

Institutions: Aston University, University of Tennessee Health Science Center

Language: English

Topic: Synthesis and biological activity

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2314525244

FWCI: 0.594

Cites: 25

Cited by: 10

Related to: 10