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The Impact of Histologic Grade on Acute Graft Versus Host Disease Response and Outcomes

Year: 2015
Type: article
Abstract: Acute graft versus host disease (GVHD) is a major cause of morbidity and mortality after allogeneic hematopoietic cell transplantation (HCT). Based on established consensus grading criteria, a correlation between clinical grading and survival has been well established. A histologic grading system for acute GVHD of the skin and gastrointestinal (GI) tract has also been well established, and is routinely used by pathologists when reporting this diagnosis. There are limited data, however, on the correlation of the histologic grade with clinical grade and its ability to predict outcome.
DOI: 10.1016/j.bbmt.2014.11.543
Authors: Mayur Narkhede, Lisa Rybicki, Donna Abounader, Steven Andresen, Brian Bolwell, Robert M. Dean, Hien K. Duong, Aaron Gerds, Rabi Hanna, Brian Hill, Deepa Jagadeesh, Matt E. Kalaycio, Brad Pohlman, Ronald Sobecks, Navneet S. Majhail, Betty Ky Hamilton
Institution: Cleveland Clinic
Language: English
Subfield: Hematology
Field: Medicine
Open Access status: hybrid
Estimated APC paid: $3,650
OpenAlex ID: W2316604799
FWCI:
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Related to: 10