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The interplay between lnRNAs, SNPs, and protein complexes - what does it mean for cancer metabolism?

Year: 2016
Type: article
Abstract: Long non-coding RNAs (lncRNAs) exert most of their functions through protein interactions. A better understanding of these interactions will facilitate the development of novel therapeutics. Recently, we described how the lncRNA CCAT2 located at the 8q24 cancer amplicon reprograms cancer metabolism by directly interacting in an allele-specific manner with a protein complex.
DOI: 10.1080/23723556.2016.1166308
Language: English
Subfield: Cancer Research
Open Access status: bronze
Funders: RGK Foundation, CLL Global Research Foundation, AIM at Melanoma, Laura and John Arnold Foundation, National Institutes of Health, University of Texas MD Anderson Cancer Center, National Cancer Institute, Moonshot Research and Development Program
Awards: G1852139970, G1943345356, G2265115783, G5974234380, G6344965762, G7905850378, G816327597, G841006155, SPORE in Brain Cancer
OpenAlex ID: W2317739367
FWCI: 0.121
Cites: 10
Cited by: 4
Related to: 10