Transplant Outcomes in Older Patients Are Comparable to Outcomes in Younger Patients after Hopkin's Non-Myeloablative Flu Cy TBI + PT-Cy Regimen
Year: 2015
Type: article
Abstract: Hematologic malignancies are largely diseases of older age. Advances in graft versus host disease (GVHD) prophylaxis utilizing post-transplant cyclophosphamide (PTCy) expanded the use of haploidentical hematopoietic cell transplantation and has encouraging results in non-haploidentical hematopoietic cell transplantation as well. The Hopkins' regimen using fludarabine, cyclophosphamide, total body irradiation and post-transplant cyclophosphamide (FluCyTBI-PTCy) has been associated with low toxicity, and low rates of acute and chronic GVHD.
Institution: Washington University in St. Louis
Language: English
Subfield: Hematology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Estimated APC paid: $3,650
OpenAlex ID: W2317857005