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NK Cell Recovery and Costimulatory Molecule Profiles After Autologous Hematopoietic Cell Transplantation (HCT) in Multiple Myeloma (MM) Patients

Year: 2013
Type: article
Study design: Observational Study
Abstract: Enhanced immune responses post autologous HCT is known to be beneficial for long term disease control in MM. Early responses are mediated by NK cells and alternate inhibitory/stimulatory pathways that include the costimulatory molecules. This pilot study assesses the expression of NK cytolytic receptor (CD16) as well as the stimulatory (OX-40, ICOS, 4-1BB, CD28, NKG2D) and inhibitory (PD-1 and CTLA-4) molecules on NK cells after auto-HCT in MM patients.
DOI: 10.1016/j.bbmt.2012.11.224
Authors: Myo Htut, Ghislaine Gallez-hawkins, Joycelynne Palmer, Ricardo Spielberger, Pablo M. Parker, Len T. Farol, Anne Franck, Laetitia Jeannet, Eunicia Reburiano, Valerie Jimenez, Lupe Duarte, Andy Dagis, Firoozeh Sahebi, Chatchada Karanes, Stephen J. Forman, Amrita Y. Krishnan, John Zaia
Language: English
Subfield: Immunology
Open Access status: hybrid
Estimated APC paid: $3,650
OpenAlex ID: W2321467640
FWCI:
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Cited by: 1
Related to: 10