Work

Central and Peripheral Autorefraction Repeatability in Normal Eyes

Year: 2014

Type: article

Abstract: PURPOSE: To determine the between-visit repeatability of peripheral autorefraction measurements using the Grand Seiko WAM-5500 in normal eyes. METHODS: Cycloplegic autorefraction of the right eye was measured on 25 myopic young adults using a modified Grand Seiko autorefractor. Measurements were made centrally (along the line of sight) and ±20, ±30, and ±40 degrees from the line of sight in the horizontal meridian at two visits separated by 1 to 15 days. Five autorefraction measurements at each location were converted to vector space and averaged. Relative peripheral refraction (RPR) was calculated as the difference between the peripheral and central spherical equivalent. Between-visit repeatability was evaluated by plotting the difference versus the mean of the measurements at the two visits (bias) and by calculating the 95% limits of agreement (LoA). RESULTS: The mean (±SD) age and spherical-equivalent refractive error centrally (at visit 1) were 24.0 ± 1.3 years and -3.45 ± 1.42 diopters (D), respectively. There was no significant between-visit bias for any refractive component evaluated (M, J0, J45, and RPR) at any location measured (all p > 0.05). The 95% LoA of defocus (M) was ±0.21 D centrally and increased with increasing eccentricity to ±0.73 and ±0.88 D at 40 degrees nasally and temporally on the retina, respectively. The 95% LoA of RPR increased with increasing eccentricity to ±0.67 and ±0.82 D at 40 degrees nasally and temporally on the retina, respectively. CONCLUSIONS: In normal eyes, the repeatability of cycloplegic autorefraction was best centrally and decreased as eccentricity increased; however, repeatability in the far periphery was still better than previously reported between-visit repeatability for foveal cycloplegic subjective refraction. With clear knowledge of the repeatability of on- and off-axis cycloplegic autorefraction with the Grand Seiko, peripheral measurements can be properly interpreted in longitudinal studies.

Source: Optometry and Vision Science

DOI: 10.1097/opx.0000000000000351

Authors: Kelly E. Moore, David A. Berntsen

Institution: University of Houston

Language: English

Topic: Ophthalmology and Visual Impairment Studies

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, National Eye Institute