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Recovery of Circulating T-Follicular Helper Cells after Hematopoietic Stem Cell Transplantation

Year: 2015
Type: article
Abstract: T-Follicular Helper Cells (TFH) interact with B-cells in the germinal center to support B-cell proliferation, differentiation and immunoglobulin gene class switch. TFH have been reported to alter B-cell homeostasis in autoimmune diseases (Morita et al, Immunity 2011) and to contribute to murine chronic graft-vs.-host-disease (GVHD) (Flynn et al, Blood 2014). However, the role of TFH in immune reconstitution and GVHD after human hematopoietic stem cell transplantation (HSCT) has not been studied.
DOI: 10.1016/j.bbmt.2014.11.240
Authors: Edouard Forcade, Steven Paula, Kristen Cowens, Marta Leal Bento, Sarah Nikiforow, John Koreth, Corey S. Cutler, Vincent T. Ho, Philippe Armand, Edwin P. Alyea, Robert J. Soiffer, Joseph H. Antin, Bruce R. Blazar, Jerome Ritz
Language: English
Subfield: Hematology
Field: Medicine
Open Access status: hybrid
Estimated APC paid: $3,650
OpenAlex ID: W2321904531
FWCI:
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