Work

Asymmetric inheritance of mTORC1 kinase activity during division dictates CD8+ T cell differentiation

Year: 2016

Type: article

Source: Nature Immunology

DOI: 10.1038/ni.3438

Authors: Kristen N Pollizzi, Im-Hong Sun, Chirag H Patel, Ying-Chun Lo, Min-Hee Oh, Adam T Waickman, Ada J Tam, Richard L Blosser, Jiayu Wen, Greg M Delgoffe, Jonathan D Powell

Institutions: National Institutes of Health, Johns Hopkins University, Johns Hopkins Medicine, Yale University, National Cancer Institute, Sidney Kimmel Comprehensive Cancer Center, University of Pittsburgh

Language: English

Topic: T-cell and B-cell Immunology

Subfield: Immunology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, National Cancer Institute, National Institute of Allergy and Infectious Diseases, National Center for Research Resources

Awards: G1165598027, Zeiss LSM780 Confocal Microscope for a Core Facility, Request for Zeiss LSM 510 MP Multiphoton Imaging System, A central role for mTOR in Determining T Cell Activation versus Tolerance, Transplantation tolerance and immune function following mTOR inhibition., G74670900

OpenAlex ID: W2321920454

FWCI: 17.5

Cites: 39

Cited by: 231

Related to: 10