The Graft-Versus-Lymphoma Effect in Diffuse Large B-Cell Lymphoma
Year: 2015
Type: article
Abstract: Diffuse large B-cell lymphoma (DLBCL) is the most frequent lymphoma in the adult population, representing 25-35% of new non-Hodgkin lymphoma cases each year (Cultrera & Dalia, 2012). Autologous hematopoietic stem cell transplant (HSCT) is the standard of care after relapse following conventional treatment, with a curative potential of 25-50%, but recurrences are common. Allogeneic HSCT represents a salvage option through the benefit of graft-versus-lymphoma effect. The role of allogeneic HSCT in patients with advanced DLBCL still remains to be defined.
Institutions: University of Michigan, University of Pennsylvania
Language: English
Subfield: Pathology and Forensic Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Estimated APC paid: $3,650
OpenAlex ID: W2321972424