Work

Antiretroviral Drug Resistance Among Children and Youth in the United States With Perinatal HIV

Year: 2016

Type: article

Study design: Observational Study

Abstract: Among 234 US youths with perinatal human immunodeficiency virus, 75% had antiretroviral resistance, substantially higher than that of the reference laboratory overall (36%-44%). Resistance to newer antiretrovirals and to all antiretrovirals in a class was uncommon. The only factor independently associated with future resistance was a higher peak viral load.

Source: Clinical Infectious Diseases

DOI: 10.1093/cid/ciw213

Authors: Russell B. Van Dyke, Kunjal Patel, Ron M. Kagan, Brad Karalius, Shirley Traite, William A. Meyer, Katherine K. Tassiopoulos, George R. Seage, Lorna M. Seybolt, Sandra Burchett, Rohan Hazra

Institutions: Tulane University, Harvard University, Quest Diagnostics (United States), Louisiana State University Health Sciences Center New Orleans, Eunice Kennedy Shriver National Institute of Child Health and Human Development

Language: English

Topic: HIV/AIDS drug development and treatment

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: U.S. Department of Health and Human Services, University of Miami, Tulane University, Harvard T.H. Chan School of Public Health, Quest Diagnostics, National Institutes of Health, University of California, San Diego, University of Colorado Denver, National Institute on Alcohol Abuse and Alcoholism, National Heart, Lung, and Blood Institute, National Institute of Mental Health, National Institute on Drug Abuse, National Institute on Deafness and Other Communication Disorders, National Institute of Allergy and Infectious Diseases, National Institute of Neurological Disorders and Stroke, National Institute of Child Health and Human Development, National Institute of Dental and Craniofacial Research, Office of AIDS Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development

Awards: G1121950248, G1526836824, G1579334765, G2106924369, G3215336396, G3723406741, G4605344243, Pediatric HIV/AIDS Cohort Study (PHACS) Coordinating Center (CC) (U01), Pediatric HIV/AIDS Cohort Study (PHACS): Data and Operations Center (DOC)., G8402651462, G8582443069

OpenAlex ID: W2328951415

FWCI: 5.229

Cites: 12

Cited by: 33

Related to: 10