Mp49-19 Comparative Evaluation of Health Related Quality of Life (hrqol) Instruments for Bladder Cancer.
Year: 2016
Type: article
Study design: Observational Study
Abstract: You have accessJournal of UrologyBladder Cancer: Invasive III1 Apr 2016MP49-19 COMPARATIVE EVALUATION OF HEALTH RELATED QUALITY OF LIFE (HRQOL) INSTRUMENTS FOR BLADDER CANCER. Travis Moncrief, Priya Balaji, Bruce Lindgren, and Badrinath Konety Travis MoncriefTravis Moncrief More articles by this author , Priya BalajiPriya Balaji More articles by this author , Bruce LindgrenBruce Lindgren More articles by this author , and Badrinath KonetyBadrinath Konety More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2016.02.432AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Orthotopic neobladder (ON) and ileal conduit (IC) are common urinary diversions performed after radical cystectomy (RC) for bladder cancer. Previous HRQOL studies in cystectomy patients have yielded conflicting results. Using a cross sectional study design we examined the only two validated Bladder Cancer Specific HRQOL (BCSHRQOL) measures. A third instrument, the EORTC-QLQ-BLM30 was excluded as it had not been explicitly validated at the time of study initiation. The aim of this study was to determine if we would find similar results using different BCSHRQOL instruments in the same patient population. METHODS Of the 206 patients who had undergone RC from 2009-2014, 156 were identified who were at least 1 year post cystectomy. Patients were excluded if they had recurrent disease, died or could not be contacted. Two BCSHRQOL instruments, the Functional Assessment Cancer Therapy-Vanderbilt Cystectomy Index (FACT-VCI) and Bladder Cancer Index (BCI) were mailed to these patients. Overall HRQOL and individual domain scores were compared between the two instruments with a Spearman correlation coefficient. HRQOL scores were compared by urinary diversion type as well using a two sample t-test. RESULTS 64 of 156 surveys were returned for a response rate of 41%. 31 had an IC while 33 had an ON. There were no significant demographic differences between the two groups. Overall, there was a moderate correlation between the FACT-VCI and BCI survey (r=0.57, p<0.001). Comparison of individual domains between each survey revealed that responses on the BCI domains were strongly correlated with responses on the bladder cancer specific domain of the FACT VCI (r=0.74, p<0.001). The BCI scores for urinary function were significantly better in the IC group (p=0.002) while the bowel and sexual function scores were not significantly different. No significant difference was found between IC and ON using the FACT VCI CONCLUSIONS These two BCSHRQOL instruments correlate well within the same patient cohort but capture different aspects of HRQOL. By focusing exclusively on bladder cancer treatment concerns the BCI appears to be a better tool for assessing and counseling patients on expected treatment specific changes after diversion type. In contrast, the FACT portion of the FACT VCI provides a more general measure of HRQOL. This likely accounts for the lack of difference in HRQOL found between the IC and ON groups. These data suggest that BCSHRQOL assessment vary based on the instrument used. Specifically, the BCI appears to better capture the difference in HRQOL experienced by patients after RC. © 2016FiguresReferencesRelatedDetails Volume 195Issue 4SApril 2016Page: e671 Advertisement Copyright & Permissions© 2016MetricsAuthor Information Travis Moncrief More articles by this author Priya Balaji More articles by this author Bruce Lindgren More articles by this author Badrinath Konety More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...
Source: The Journal of Urology
Institution: University of Minnesota
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W2329081093