Trichosetin, a Novel Tetramic Acid Antibiotic Produced in Dual Culture of Trichoderma harzianum and Catharanthus roseus Callus
Year: 2002
Type: article
Abstract: The dual culture of Trichoderma harzianum and Catharanthus roseus callus produced an antimicrobial compound with a remarkable activity against the Gram-positive bacteria Staphylococcus aureus and Bacillus subtilis. Structural elucidation revealed that this compound, which we have named trichosetin, is a novel tetramic acid (2,4-pyrrolidinedione) antibiotic and a homolog of the fungal metabolite equisetin. This compound however, was not produced in the individual culture of T. harzianum or C. roseus callus.
Source: Zeitschrift für Naturforschung C
Authors: Eufrocinio C. Marfori, Shin’ichiro Kajiyama, Ei-ichiro Fukusaki, Akio Kobayashi
Institution: The University of Osaka
Language: English
Subfield: Pharmacology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Estimated APC paid: $2,712
OpenAlex ID: W2329579819