Work

Outcome after Allogeneic Stem Cell Transplant for Patients with Hematological Malignancies and Associated Chromosome 7 Deletions

Year: 2014

Type: article

Abstract: Chromosome 7 deletions are adverse prognostic factors associated with worse outcomes in patients with hematological malignancies. However there are few outcome data for hematopoietic stem cell transplant (HSCT) in pediatric patients with hematological malignancies and chromosome 7 deletions. We now describe the outcome in 40 patients with chromosome 7 abnormalities (ALL, n=13, AML, n=11, MDS, n=14 and JMML, n=2) who received an allogeneic HSCT at our institution between 2001-2013. The median age at the time of transplant was 9 years (range: 1-18 years).

Source: Transplantation and Cellular Therapy

DOI: 10.1016/j.bbmt.2013.12.290