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Pd15-09 Outcomes After Implementation of Software Fusion Mri-targeted Biopsy: Is Fusion Better Than Cognitive Targeting?

Year: 2016

Type: article

Abstract: 8/20 patients with lesions identified retrospectively.On multivariate analysis, lower PSA (p <.001), higher MR prostate volume (p<.001), and lower number of target cores (p<.001) were independent predictors of upgrading by SBx.CONCLUSIONS: MRI rarely misses CS CaP lesions and FBx, if accurate, should reflect the true disease state.Most upgrading by SBx was to low risk, low volume CaP.In patients upgraded by SBx to CS CaP, mpMRI identified a targetable lesion within the SBx sextant in a majority of patients.FBx failure may be related to suboptimal imaging or biopsy related inaccuracy including registration error or mechanical error.Other possibilities include presence of tumor heterogeneity, multifocality within the same sextant, or low volume disease.Future studies with biopsy mapping on MRI will provide insight into mechanisms of failure in patients with overlapping target and sextant sampling.

Source: The Journal of Urology

DOI: 10.1016/j.juro.2016.02.1135

Authors: Eric Kim, Joel Vetter, John Weaver, Niraj Badhiwala, Michael Glamore, Robert Grubb, Gerald Andriole

Language: English

Topic: Prostate Cancer Diagnosis and Treatment

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: Foundation for the National Institutes of Health, Howard Hughes Medical Institute, Doris Duke Charitable Foundation, Pfizer, National Institutes of Health, National Cancer Institute

OpenAlex ID: W2329802601

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