Year: 2013
Type: article
Abstract: Cardiovascular malformations are the most common and deadly of birth defects in humans and unfortunately very little are known of their genesis and few treatment options are currently available.Furthermore, numerous "Adult" cardiovascular diseases (CVDs) have their origins in embryonic development.For some CVDs this is developmental origin is straightforward as is the case with bicuspid aortic valves.However, in other CVDs such as aortic aneurisms, the role of dysmorphogenesis is not well appreciated.Thus, determining the cellular and molecular mechanisms of cardiovascular development will enable novel pharmacological and cellular therapies to treat these devastating and debilitating disorders.
Source: Microscopy and Microanalysis
Authors: R.L. Goodwin, A.N. Evans, L. Junor, S.V. Biechler, M.M. Yost, V. Krishnamurthy, R.B. Hinton, K. Maddy, J.D. Potts
Language: English
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: bronze
OpenAlex ID: W2330151909