Work

Assessing Differential Drug Effect

Year: 1984
Type: article
Abstract: The regression effect gives a misleading impression of the relationship between drug or treatment effect and baseline measurement. We propose a method of adjusting for the regression effect; we also suggest a corresponding test for the differential drug effect. The likelihood ratio test for no differential drug effect is equivalent to a test for equality of variances, suggested by Pitman (1939, Biometrika 31, 9-12) and Morgan (1939, Biometrika 31, 13-19). The proposed adjustment and test are applied to an example of blood pressure data.
Source: Biometrics
Language: English
Open Access status: green
OpenAlex ID: W4299962144
FWCI: 1.351
Cites: 3
Cited by: 28
Related to: 10