Work

Secreted microRNAs from tumor cells can suppress immune function

Year: 2016

Type: article

Abstract: Our recent study reported an interesting finding that tumor cells can actively manipulate host immune function to facilitate tumor immune escape through the secretion of microRNAs (miRNAs). As an extension of this finding, we showed that blockage of the function of tumor-secreted miRNAs represents an effective therapeutic approach for cancer treatment.

Source: OncoImmunology

DOI: 10.4161/2162402x.2014.982407

Authors: Xi Chen, Hongwei Liang, Ke Zen, Chen-Yu Zhang

Institutions: Nanjing University of Science and Technology, State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University

Language: English

Topic: MicroRNA in disease regulation

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,913