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Inside Back Cover: A Multi‐RNAi Microsponge Platform for Simultaneous Controlled Delivery of Multiple Small Interfering RNAs (Angew. Chem. Int. Ed. 10/2016)

Year: 2016

Type: article

Abstract: RNA interference (RNAi) has been intensively investigated as a powerful approach for therapeutic applications. In their Communication on page 3347 ff., P. T. Hammond et al. describe a modular platform for generating multiple polymeric RNAi molecules that self-assemble and densely pack to form composite sponge-like porous microstructures. The picture illustrates the precise ratiometric formation of microstructures from two polymeric RNAi molecules.

Source: Angewandte Chemie International Edition

DOI: 10.1002/anie.201600877

Authors: Young Hoon Roh, Jason Z. Deng, Erik C. Dreaden, Jae Hyon Park, Dong Soo Yun, Kevin E. Shopsowitz, Paula T. Hammond

Institutions: Yonsei University, Koch Institute for Integrative Cancer Research At MIT, Massachusetts Institute of Technology

Language: English

Topic: RNA Interference and Gene Delivery

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: bronze

OpenAlex ID: W2330918076

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