Mp63-07 the Association Between Preoperative Leukocytosis and Postoperative Outcomes Following Cystectomy for Bladder Cancer
Year: 2016
Type: article
Study design: Observational Study
Abstract: significant in univariate analysis to identify predictors of perioperative (during hospital stay) morbidity and infection.Composite morbidity included hospital-acquired infection (13%) thrombotic (3.9%), renal (2.9%), ischemic (1%) or respiratory (1%) adverse events.Hospitalacquired infection included post-op infection (8.3%), Clostridium difficile (5.4%), sepsis (2%) and drug-resistant infection (0.05%).RESULTS: Similar to existing RCTs, with a cutoff of 21 days, we found no statistically significant difference in infection or morbidity.For 28 days, old blood independently predicted perioperative morbidity (HR 3.4 (1.5-8.5),p¼0.004).For 35 days, old blood independently predicted infection (HR 4.3 (1.4-12.8),p¼0.011), as well as morbidity (HR 6.2 (2.3-16.9),p¼0.0004).CONCLUSIONS: In conclusion, longer duration blood storage, especially 35 days, may be suboptimal and expose our bladder cancer patients to potential harm as demonstrated by increased morbidity and infectious complications in the post-operative setting.
Source: The Journal of Urology
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W2332230740