Mp80-05 Nerve Sparing During Radical Prostatectomy Does Not Adversely Impact Margin Status, Complications, or Long-term Oncologic Outcomes
Year: 2016
Type: article
Study design: Observational Study
Abstract: older than 50 years were not significant.Robotic status did not affect OF, whereas bilateral nerve sparing significantly improved the likelihood of good OF compared to non-nerve sparing (OR ¼ 5.00; CI 1.61-15.6;p ¼ 0.04).The odds for patients with poor preoperative OF to achieve good postoperative OF was only 8.2% of that for men with good preoperative OF (p < 0.001).The effect of age, nerve sparing status, and preoperative OF persisted in subgroup analysis of 356 patients with > 21 months follow up (all p < 0.002).Good postoperative OF was positively associated with good erectile function (EF) (OR ¼ 43.7; CI 25.2-75.9;p < 0.001) and sexual desire (OR ¼ 5.1; CI 3.8-6.8;p < 0.001) but negatively associated with moderate to severe urinary incontinence (OR ¼ 0.32; CI 0.19-0.54;p < 0.001) and lower urinary tract symptoms (OR ¼ 0.63; CI 0.47-0.84;p ¼ 0.002).Patients who were bothered by their EF were also likely to be bothered by their OF (OR ¼ 189; CI 107-336; p < 0.001).However, use of erectile aids was not significantly related to OF (p ¼ 0.06-0.58).In subgroup analysis of men with > 21 months follow up who had poor postoperative EF, the association of age 50 years (OR ¼ 3.849; CI 1.136-13.044;p ¼ 0.03) and bilateral nerve sparing (OR ¼ 3.268; CI 1.355-7.882;p ¼ 0.008) with good OF persisted, suggesting their independent effect on OF apart from that on EF.CONCLUSIONS: Orgasmic function is negatively impacted by radical prostatectomy and takes 15 to 21 months to recover.Predictors of orgasmic function include age, nerve sparing status, preoperative orgasmic function, erectile function, sexual desire, and urinary control and function.
Source: The Journal of Urology
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W2333801166