Work

Clinical use of statins in hematopoietic stem cell transplantation: Old drugs and new horizons.

Year: 2016

Type: article

Abstract: Hydroxymethylglutaryl Co-enzyme A reductase inhibitors, also known as statins, are a class of anti-hyperlipidemic agents. These drugs have been employed vastly to reduce the morbidity and mortality of cardiovascular disorders. Soon after their introduction, benefits other than their primary actions were discovered. Along with these pleiotropic properties, a series of mainly favorable effects has been proposed in patients intended to undergo hematopoietic stem cell transplantation. These actions address some complications encountered by this special population such as graft-versus-host disease, efficacy of chemotherapy, infections, etc. This review presents the current evidence surrounding these issues.

Source: PubMed Central

Authors: Mehdi Mohammadi, Mohammad Vaezi, Bahador Mirrahimi, Molouk Hadjibabaie

Institutions: Tehran University of Medical Sciences, Shahid Beheshti University, Shahid Beheshti University of Medical Sciences

Language: English

Topic: Hematopoietic Stem Cell Transplantation

Subfield: Hematology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2337384036

FWCI: 0.766

Cites: 53

Cited by: 8

Related to: 10