Adjusting the polymerization time of isobutyl-2 cyanoacrylate.
Year: 1986
Type: article
Abstract: Isobutyl-2 cyanoacrylate (IBCA) polymerizes by an anionic mechanism. The initiation of polymerization depends on an alkaline medium and can be inhibited with the addition of small amounts of acid. Using small amounts of glacial acetic acid (3.7%-7.1% by volume), the polymerization time was prolonged from 2.3 sec to 7.8 sec. In vivo experiments in dogs demonstrated no additional inflammatory reactions to the mixture of IBCA, iophendylate, and tantalum powder when acetic acid was added. Glacial acetic acid offers a safe and effective way, without increase in viscosity, to manipulate the polymerization time of IBCA.
Source: PubMed
Authors: S M Spiegel, F Viñuela, J M Goldwasser, A J Fox, D M Pelz
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2340474905