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Spiroergometryczna ocena wydolności wysiłkowej u dorosłych pacjentów po korekcji całkowitej tetralogii Fallota

Year: 2005
Type: article
Study design: Observational Study
Abstract: Background: Total correction of tetralogy of Fallot enables the majority of patients to reach adulthood. In long-term follow-up, 10-20% adults presented signs and symptoms of heart failure. The goal of the study was to assess physical capacity of adult patients with tetralogy of Fallot using spiroergometry as well as establishing potential relationship between these data and chosen echocardiographic parameters, highlighting degree of pulmonary regurgitation, significance of history of palliative procedure and total correction of the anomaly. Material and methods: We analyzed 63 asymptomatic patients aged 27.7 ± 7.1 years, operated on at the average age of 7.4 ± 5.1 years, 20.7 ± 5.7 years ago. 76.2% of patients underwent transannular patch repair. In 16 (25.3%) subjects palliative procedure was per- formed in the past. The control group consisted of 28 individuals aged 28.7 ± 5.1 years. On echocardiography (M, 2D, Doppler modes), right (RVEDD) and left (LVEDD) ventricular end diastolic diameters were measured, and subsequently, right to left ventricular dimensions ratio (RV/LV) was calculated, as well as left ventricular ejection fraction (LVEF), right ventricular systolic pressure (RVSP), degree of right ventricular outflow tract obstruction (RVOT-PG), severity of the pulmonary regurgitation (PR). All patients carried out a maximal treadmill exercise test according to modified Bruce protocol. The maximal oxygen consumption (peak VO2), VE/VCO2 slope, forced vital capacity (FVC), forced expiratory volume in one second (FEV1) were measured. Results: VO2 in study group was lower than in control group: 24.9 ± 5.7 vs. 36.6 ± 7.6 ml/ /kg/min (p = 0.00001). Systolic blood pressure on peak of exercise was 148.7 ± 24.5 mm Hg and was lower than measured in the control group: 168.9 ± 15.3 mm Hg (p = 0.0006).
Language: Polish
Field: Medicine
Open Access status: diamond
OpenAlex ID: W2341404902
FWCI:
Cites: 33
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Related to: 10