Proteomic Findings in Melanoma
Year: 2016
Type: article
Abstract: Although the emergence of proteomics as an independent branch of science is fairly recent, within a short period of time it has contributed substantially in various disciplines. The tool of mass spectrometry has become indispensable in the analysis of complex biological samples. Clinical applications of proteomics include detection of predictive and diagnostic markers, understanding mechanism of action of drugs as well as resistance mechanisms against them and assessment of therapeutic efficacy and toxicity of drugs in patients. Here, we have summarized the major contributions of proteomics towards the study of melanoma, which is a deadly variety of skin cancer with a high mortality rate.
DOI: 10.4172/jpb.1000e29
Authors: Deepanwita Sengupta, Alan J Tackett
Institution: University of Arkansas for Medical Sciences
Language: English
Subfield: Spectroscopy
Field: Chemistry
Domain: Physical Sciences
Open Access status: green
Awards: Partnerships for Biomedical Research in Arkansas, Arkansas Center for Clinical and Translational Research, Center for Microbial Pathogenesis and Host Inflammatory Responses, Using ChAP-MS to Study Macromolecular Chromatin Composition during Transcription, Orbitrap Fusion Tribrid Mass Spectrometer, Development of MassSQUIRM to Quantitatively Measure Lysine Methylation
OpenAlex ID: W2344877421