Evaluation of Cerebral Hemodynamics in Cirrhotic Patients by Transcranial Doppler Ultrasonography and its Relation to Hepatic Encephalopathy
Year: 2016
Type: article
Study design: Observational Study
Abstract: The study aimed at Aim evaluation the cerebral hemodynamics in cirrhotic patients by transcranial Doppler ultrasonography and its relation to hepatic encephalopathy.This study is a prospective study , 50 subjects attended El Hussein university hospital, inpatient and outpatient clinic are classified into three groups, group I(10 subjects as a healthy control),group II (20 subjects with liver cirrhosis without hepatic encephalopathy) and group III(20 subjects with liver cirrhosis with hepatic encephalopathy).All patients included in the study underwent a full history taking,complete physical examination, liver functions tests,blood ammonia level,C.B.C,blood urea and serum creatinine and pelvi-abdominal ultarasonography.Transcranial Doppler done for all patients participated in the study using a 2 MHz transducer.The results showed that as regard Trans cranial Doppler ultrasound parameters, we found a statistical significant difference between the three groups as regard Pulsatility Index (P ˂ 0.001), Breath-Holding Index (P ˂ 0.001) ) , Maximum Flow Velocity(P ˂ 0.001) and Mean (P ˂ 0.001), whereas Pulsatility Index, , Maximum Flow Velocity and Mean are higher in patient with Hepatic Encephalopathy, but Breath-holding index is low, there is no statistical significant difference (P > 0.05) between them as regard Minimum Flow Velocity.Conclusion: Transcranial doppler ultrasonography is easy, rapidly done not invasive method for evaluation of cerebral hemodynamic in cirrhotic patient and predection of hepatic encephalopathy.
Language: English
Subfield: Hepatology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2344892702