The influence of changes in tension on protein synthesis and prostaglandin release in isolated rabbit muscles
Year: 1983
Type: article
Abstract: Intermittent stretching of isolated rabbit muscles increased the rate of protein synthesis by 70% and prostaglandin-F2 alpha release by 105%. Both effects of intermittent stretching were blocked by indomethacin and meclofenamate; the absence of Ca2+ together with added EGTA also inhibited both processes. The residual influence of intermittent stretching on protein synthesis was closely correlated with prostaglandin-F2 alpha release, which may be the link between mechanical activity and protein synthesis in skeletal muscle.
Source: Biochemical Journal
DOI: 10.1042/bj2141011
Authors: R M Palmer, P J Reeds, T Atkinson, R H Smith
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: bronze
OpenAlex ID: W2345734345