Year: 2016
Type: article
Abstract: Apigenin, a flavonoid compound has been isolated from the ethyl acetate fraction of methanol extract of Macaranga gigantifolia leaves. Isolation and purification of apigenin conducted using chromatographic method, and chemical structure characterized based on spectroscopic data. In vitro anticancer activity test against murine leukemia P-388 cell line showed potential activity with IC50 14.13 μg/mL.Key words: apigenin, flavones, Macaranga gigantifolia, anticancer, murine leukemia P-388 cell line.
Source: Journal of Tropical Life Science
Authors: Sofa Fajriah, Megawati Megawati, Akhmad Darmawan
Institution: Indonesian Institute of Sciences
Language: English
Topic: Bioactive natural compounds
Subfield: Drug Discovery
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $196
OpenAlex ID: W2346339589