Work

Cytotoxic Constituents from the Stem Bark of Alvaradoa amorphoides

Year: 2017

Type: article

Abstract: The chemical study of Alvaradoa amorphoides led to the isolation of four major constituents: chrysophanol (1), β-sitosterol (2), atraric acid (3), and 17-octadecen-6-ynoic acid (4). All compounds were evaluated on in vitro cytotoxic and antiproliferative assays. Atraric acid and 17-octadecen-6-ynoic acid showed cytotoxic activity. Additionally, compound 4 exhibited cytotoxic activity showing a certain degree of selectivity against cancer cell lines.

Source: Journal of the Mexican Chemical Society

DOI: 10.29356/jmcs.v59i3.37

Author: Sergio R. Peraza-Sanchez

Institution: Centro de Investigación Científica de Yucatán, A.C

Language: English

Topic: Phytochemical Studies and Bioactivities

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: diamond

Funder: Consejo Nacional de Ciencia y Tecnología