Work

The spectrum effect in tests for risk prediction, screening, and diagnosis

Year: 2016

Type: article

Abstract: The spectrum effect describes the variation between settings in performance of tests used to predict, screen for, and diagnose disease. In particular, the predictive use of a test may be different when it is applied in a general population rather than in the study sample in which it was first developed. This article discusses the impact of the spectrum effect on measures of test performance, and its implications for the development, evaluation, application, and implementation of such tests.

Source: BMJ

DOI: 10.1136/bmj.i3139

Authors: Juliet A Usher-Smith, Stephen J Sharp,, Simon J Griffin

Institutions: University of Cambridge, MRC Epidemiology Unit

Language: English

Topic: Statistical Methods in Epidemiology

Subfield: Statistics and Probability

Field: Mathematics

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $4,654