Production of artemisinin by Artemisia annua hairy root culture in a internal loop airlift bioreactor
Year: 1999
Type: article
Abstract: A self-made internal loop airlift bioreactor was used for production of artemisinin by Artemisia annua L. hairy root multi-plate culture. The hairy root cultures grew evenly either between the two meshes or attaching to the stainless steel meshes in the bioreactor. Under the optimal conditions of 12 h/d light cycle and 25 degrees C, the dry weight and artemisinin yield reached 22.57 g/L and 374.4 mg/L respectively after 20 days. Meantime, the kinetics of sugar, phosphate, nitrate and ammonium uptake during the course of culture were studied.
Authors: Liu, CZ, Wang, YC, Ouyang, F, Ye, HC, Li, GF
Language: English
Subfield: Plant Science
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W2353727276
