Effect of combination therapy of omeprazole,amoxicillin and clarithromycin on gastric ulcer
Year: 2015
Type: article
Study designs: Randomized Controlled Trial, Clinical Trial
Abstract: Objective To observe the effect of omeprazole,amoxicillin combined with clarithromycin on gastric ulcer.Methods One hundred cases of gastric ulcer admitted in central hospital of Yongcheng from July 2012 to November 2013 were selected as research subjects,and randomly divided into observation group and control group( fifty cases in each group). The observation group was treated with combination treatment of omeprazole,amoxicillin and clarithromycin,and the control group was treated with omeprazole,amoxicillin and metronidazole. Results The occurrence of discomfort of the two groups were compared,and the incidence in the observation group was significantly lower than that in the control group. The excellent cases in observation group was 39,accounting for 78. 00%,the rate of excellent and good was 98. 00%( 49 /50). Both of them were significantly higher than that of control group,which were 56. 00%( 28 /50) and 80. 00( 40 /50). The differences were statistically significant( P 0. 05). Conclusion The combination of omeprazole,amoxicillin and clarithromycin can effectively relieve symptoms and reduce the economic burden of the family,so it is worthy of recommendation clinically.
Source: Clinical Medicine
Author: Zhuang Gui-xian
Institution: Yuncheng Central Hospital
Language: English
Subfield: Gastroenterology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,500
OpenAlex ID: W2378588127