Work

Burns: Pathophysiology of Systemic Complications and Current Management

Year: 2016

Type: review

Abstract: As a result of many years of research, the intricate cellular mechanisms of burn injury are slowly becoming clear. Yet, knowledge of these cellular mechanisms and a multitude of resulting studies have often failed to translate into improved clinical treatment for burn injuries. Perhaps the most valuable information to date is the years of clinical experience and observations in the management and treatment of patients, which has contributed to a gradual improvement in reported outcomes of mortality. This review provides a discussion of the cellular mechanisms and pathways involved in burn injury, resultant systemic effects on organ systems, current management and treatment, and potential therapies that we may see implemented in the future.

Source: Journal of Burn Care & Research

DOI: 10.1097/bcr.0000000000000355

Authors: Colton B. Nielson, Nicholas C. Duethman, James M. Howard, Michael Moncure, John G. Wood

Institution: University of Kansas Medical Center

Language: English

Topic: Burn Injury Management and Outcomes

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $3,698