Relationship between the serum c-reactive protein concentration and insulin resistance in type 2 diabetic patients
Year: 2008
Type: article
Study design: Observational Study
Abstract: Background/Aims : Low grade inflammation has been suggested to be a risk factor for development of atherosclerosis. C-reactive protein (CRP) is very sensitive acute phase reactant, and it is considered as an important marker of atherosclerosis and related disorder. Insulin resistance is also known to be associated with atherosclerosis. However, the relationship between insulin resistance and CRP has not been thoroughly studied in patients with type 2 diabetes. This study aimed to determine whether insulin resistance in type 2 diabetes is related with CRP. Methods : 102 subjects with type 2 diabetes were included in the study. Fasting blood samples were taken for measurement for CRP, insulin and glucose. To estimate insulin resistance, the HOMA (homeostasis model assessment)-IR (insulin resistance) was calculated by the standard formula. We divided the subjects into two groups depending on their CRP levels (Group A:
Authors: Soyoung Kim, Su Jin Jeong, Heung-Yong Jin, Chong Hwa Kim, Hong-Sun Baek, Taesun Park, Jihyun Park
Institution: Jeonbuk National University
Language: English
Subfield: Endocrinology, Diabetes and Metabolism
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $500
OpenAlex ID: W2387339574