Work

In Situ Localization of WDNM1 and Ferritin Heavy Chain Gene Expression in Mammary Gland

Year: 1997

Type: article

Abstract: In situ hybridization was performed with sections obtained from mammary gland at 10 days of lactation and at 1 and 3 days of involution using either digoxigenin-labeled antisense or sense RNA probe in order to localize expression of WDNM1 and ferritin heavy chain mRNA. The WDNM1 gene was predominantly expressed in the layer of secretory epithelial cells surrounding the lumen of mammary gland alveoli. The lower levels of WDNM1 mRNA were observed at involution day 3 compared to involution day 1. The expression of ferritin heavy chain mRNA also appears to be confined to the epithelial layer of mammary alveoli. The lower levels of ferritin heavy chain mRNA were observed at involution day 3 compared to involution day 1.

Source: Molecules and Cells

DOI: 10.1016/s1016-8478(23)13320-6

Authors: Myunggi Baik, Lothar Hennighausen, Yunjaie Choi

Institutions: Chonnam National University, National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, Seoul National University

Language: English

Topic: Iron Metabolism and Disorders

Subfield: Hematology

Field: Medicine

Domain: Health Sciences

Open Access status: hybrid

Estimated APC paid: $2,500

OpenAlex ID: W2394716276

FWCI:

Cites: 1

Cited by: 2

Related to: 10