Work

Expression of pS2 gene in human breast cancer cell line MCF-7 is controlled by retinoic acid.

Year: 1992

Type: article

Abstract: We established a simplified method for the quantitative measurement of pS2 mRNA using the reverse transcriptase-polymerase chain reaction (RT-PCR) method. Expression of the pS2 gene, which is transcriptionally induced by estrogen in breast cancer cell line MCF-7 cells, can be repressed by retinoic acid (RA) in unstimulated cells. The suppressive effect of RA on pS2 mRNA was inhibited by cycloheximide.

Source: PubMed

Authors: M Hirota, Y Furukawa, K Hayashi

Language: English

Topic: Estrogen and related hormone effects

Subfield: Endocrinology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2395018297

FWCI: 0.333

Cites:

Cited by: 8

Related to: 10