Multimodal integration of simultaneous acquired EEG and fMRI data to study cognitive processes
Year: 2010
Type: conference-paper
Abstract: Several imaging modalities exist to study human brain function non-invasively, i.e. to localize and determine the temporal dynamics of neural activity without involving entry into the body. Based on the electrical origin of neural activity, electroencephalography (EEG) allows studying brain activity on a time scale similar to specific neural events (ms) by measuring electrical potentials on the scalp. Inverse techniques try to localize the underlying neural sources out of these potentials but are mostly unreliable by lack of a golden standard. Neural activity is accompanied with increased oxygen consumption. A coupled hemodynamic response supplies the active regions with oxygen rich blood. Functional magnetic resonance imaging (fMRI) identifies the regions of local increased oxygen supply and is based on the different magnetic properties of oxyhemoglobin and deoxyhemoglobin, whose concentrations reflect the blood oxygenation level. FMRI analysis obtains good spatial resolution of neural activity (mm) but the temporal resolution is limited (2-5s) (see Fig. 1).
Author: Gregor Strobbe
Language: English
Subfield: Cognitive Neuroscience
Field: Neuroscience
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W2397201054