Work

Inhibition of Rb Phosphorylation Leads to mTORC2-Mediated Activation of Akt

Year: 2016

Type: article

Source: Molecular Cell

DOI: 10.1016/j.molcel.2016.04.023

Authors: Jinfang Zhang, Kai Xu, Pengda Liu, Yan Geng, Bin Wang, Wenjian Gan, Jianping Guo, Fei Wu, Y. Rebecca Chin, Christian Berrios, Evan C. Lien, Alex Toker, James A. DeCaprio, Piotr Sicinski, Wenyi Wei

Institutions: Beth Israel Deaconess Medical Center, Harvard University, Tongji Hospital, Huazhong University of Science and Technology, Dana-Farber Cancer Institute, Army Medical University, Daping Hospital, Fudan University, Huashan Hospital, Brigham and Women's Hospital, Dana-Farber Brigham Cancer Center

Language: English

Topic: PI3K/AKT/mTOR signaling in cancer

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: National Institutes of Health, National Heart, Lung, and Blood Institute, National Cancer Institute, National Institute of General Medical Sciences

Awards: G3084427372, G311021743, G3355947620, G340051698, Training Program in Angiogenesis and Inflammation, Novel regulation of PI3K/Akt to direct targeted breast cancer therapies, G5738652912, Interplay between Cdh1 and major regulatory pathways in human cancer, G8656420957, Cyclin-Dependent Kinases in Oncogenesis

OpenAlex ID: W2397317955

FWCI: 6.019

Cites: 56

Cited by: 105

Related to: 10