Adult mesenchymal stem cells and their potency in the cell-based therapy.
Year: 2013
Type: article
Abstract: Cerebellar granule cells originate from precursors located at the dorsal region of rhombomere in the hindbrain of embryos. They undergo proliferation from embryo to post-natal period so as to form the major cell type of the cerebellum. The development of granule cell is not only highly dependent on the cerebellar intrinsic environment, but also is regulated by serials of transcription factors on different signaling pathways. Therefore, in this manuscript the signaling pathways participating in the proliferation and differentiation of granular cells during normal development was reviewed.
Source: PubMed Central
Authors: Madhurima Das, Inger Birgitta Sundell, Prasad S Koka
Institution: Haffkine Institute
Language: English
Subfield: Cell Biology
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W2397348254