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The metabolic fate of glutamine nitrogen in the perfused rat kidney

Year: 1978

Type: article

Abstract: The fate of glutamine amide and amino nitrogen was determined in the perfused rat kidney. There is a deficit of about 40% in the recovery of glutamine nitrogen and NH3 in the perfusion medium. After correction for the tissue conetent of glutamine, the remaining nitrogen was fully accounted for by small amounts of NH3, glutamate, aspartate and a compound that liberated glutamate on acid hydrolysis, probably 5-oxopyrrolidine-2-carboxylate (pyroglutamate). The latter accounted for 8% of the glutamine metabolized.

Source: Biochemical Journal

DOI: 10.1042/bj1700177

Authors: B D Ross, S Bullock

Institutions: John Radcliffe Hospital, University of Oxford

Language: English

Topic: Amino Acid Enzymes and Metabolism

Subfield: Biochemistry

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

OpenAlex ID: W2397865436

FWCI: 0.358

Cites: 6

Cited by: 5

Related to: 10